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Double Attack

A new kind of high-throughput screening may truly make drugs better, faster, cheaper.

Although physicians and pharmaceutical scientists often combine drugs when a benefit is predictable, until now, scientists had no reliable means of testing possible combinations�nor, indeed, any compelling reason to do so. In June, however, researchers at CombinatoRx published a paper in the Proceedings of the National Academy of Sciences demonstrating not only how drug combinations can be tested systematically, but also that some may have surprisingly therapeutic benefits.1

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1 Borisy, A.A., et al. (2003) Systematic discovery of multicomponent therapeutics. Proceedings of the National Academy of Sciences U.S.A. 100:7977�82.